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Select Biotechnology Portfolio

Filed by Fidelity Select Portfolios. What this fund reported holding in its latest quarterly NPORT-P. Positions are ordered by share of the fund rather than by size, because that is what separates a conviction from a rounding error.

Positions
32
matched to a ticker
Fund size
$6.6B
the filing's own figure
Matched value
$3.4B
of the positions below
As of
2026-08-31
S000007486

What it holds

Largest share of the fund first.

Company% of fundValue
ABBVAbbVie Inc10.40%$653.8M
KRYSKrystal Biotech Inc10.30%$647.8M
AMGNAmgen Inc6.98%$438.9M
MRNAModerna Inc3.49%$219.6M
INSMInsmed Inc2.41%$151.4M
ARGXargenx SE2.32%$145.9M
PRAXPraxis Precision Medicines Inc2.29%$144.1M
NTRANatera Inc1.72%$107.9M
BIIBBiogen Inc1.57%$98.9M
ALNYAlnylam Pharmaceuticals Inc1.52%$95.8M
BBIOBridgeBio Pharma Inc1.09%$68.6M
TWSTTwist Bioscience Corp1.04%$65.2M
PCVXVaxcyte Inc0.95%$59.5M
AXSMAxsome Therapeutics Inc0.90%$56.5M
COGTCogent Biosciences Inc0.89%$56.2M
MDGLMadrigal Pharmaceuticals Inc0.84%$53M
AMLXAmylyx Pharmaceuticals Inc0.79%$49.6M
UTHRUnited Therapeutics Corp0.67%$42.2M
ARWRArrowhead Pharmaceuticals Inc0.54%$33.7M
RLAYRelay Therapeutics Inc0.48%$30.2M
IONSIonis Pharmaceuticals Inc0.46%$28.8M
GPCRStructure Therapeutics Inc0.40%$24.9M
NTLAIntellia Therapeutics Inc0.39%$24.4M
BNTXBiontech SE0.34%$21.5M
VTRSViatris Inc0.32%$20.2M
TECXTectonic Therapeutic, Inc. - Common Stock0.19%$12.1M
VRTXVertex Pharmaceuticals Inc0.07%$4.4M
RAREUltragenyx Pharmaceutical Inc0.06%$3.6M
AVIRAtea Pharmaceuticals, Inc. - common stock0.02%$1.5M
CYTKCytokinetics Inc0.02%$1.4M
REGNRegeneron Pharmaceuticals Inc0.01%$799.1K
GILDGilead Sciences, Inc0.01%$796.8K

Source: NPORT-P filings, via EDGAR. Positions arrive by CUSIP, and only a CUSIP verified against a ticker is kept — so this is what we could match, not everything the fund holds, and the matched value is therefore below the fund's own size. A balance is shares where the filing says `NS` and a principal amount where it says `PA`, which is why it is not labelled shares in both cases.

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